Changes in gene expression in healthcare workers during night shifts: implications for immune response and health risks
The results revealed that innate immune and inflammatory responses are elicited after night shifts in healthcare workers and that gene expression patterns correlate with several diseases in terms of immune and inflammatory responses. These findings suggest that shift work may affect health risks through innate immune and inflammatory responses.
Authors
- Daisuke Okuzaki (ORCID: https://orcid.org/0000-0002-4552-783X)
- Tsunehiro Matsubara (ORCID: https://orcid.org/0000-0002-0910-3124)
- Shunichiro Nakao (ORCID: https://orcid.org/0000-0001-5530-806X)
- Jun Oda (ORCID: https://orcid.org/0000-0002-8254-3716)
- Shuhei Murao
- Hiroshi Ogura (ORCID: https://orcid.org/0000-0002-5013-2445)
- Mohamad Al Kadi (ORCID: https://orcid.org/0000-0002-4601-3830)
- Hisatake Matsumoto (ORCID: https://orcid.org/0000-0001-5771-570X)
- Ryota Nukiwa
- Sayaka Oda
Institutions
- Aomori Rosai Hospital (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Journal of Intensive Care
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s40560-024-00769-5
- Citations
- 2
- Primary Topic
- Sleep and Work-Related Fatigue
- Type
- article
- Field-Weighted Citation Impact
- 4.24
Funders
- Takeda Science Foundation
- Japan Society for the Promotion of Science