Young fibroblast-derived migrasomes alleviate keratinocyte senescence and enhance wound healing in aged skin
Migrasomes formation ability reduced during skin aging progress, and young fibroblast-derived migrasomes rejuvenated senescent keratinocytes and promoted wound healing in aged skin. These findings offer new ideas for alleviating skin aging and enhancing wound healing in aged skin.
Authors
- Hong Tu (ORCID: https://orcid.org/0000-0002-8298-5207)
- Yan He (ORCID: https://orcid.org/0000-0001-9067-2545)
- Yi Guo (ORCID: https://orcid.org/0000-0002-0669-9049)
- Sangang He (ORCID: https://orcid.org/0000-0001-8684-8878)
- Guoliang Sa (ORCID: https://orcid.org/0000-0002-4069-7231)
- Yingliang Shi
- Zhongyang Zou
- Jing Zhou (ORCID: https://orcid.org/0000-0001-5074-2502)
Institutions
- Wuhan University (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s12951-025-03293-2
- Citations
- 14
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 12.80
Funders
- National Natural Science Foundation of China