Deciphering distinct spatial alterations in N-glycan expression profiles in the spinal cord and brain of male rats in a neuropathic pain model
Given that N-glycans are implicated in pain processing yet their precise role remains unclear, our study highlights the need to explore N-glycosylation with a more nuanced focus on both the spinal cord and brain. This research provides new insights into the mechanisms of persistent neuropathic pain and lays the groundwork for future studies and the development of targeted therapeutic strategies.
Authors
- Hyun Jun Jang (ORCID: https://orcid.org/0000-0001-6063-3510)
- Juhee Shin (ORCID: https://orcid.org/0000-0002-8236-9551)
- Sangkyu Lee (ORCID: https://orcid.org/0000-0002-6916-3372)
- Dong Woon Kim (ORCID: https://orcid.org/0000-0001-7691-1394)
- Boyoung Lee (ORCID: https://orcid.org/0000-0001-9445-510X)
Institutions
- Kyung Hee Cyber University (KR)
- Kyung Hee University (KR)
- Institute for Basic Science (KR)
Publication Details
- Journal
- Cellular & Molecular Biology Letters
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s11658-025-00709-7
- Citations
- 1
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Research Foundation of Korea
- Institute for Basic Science