GINS4 silencing mediates hepatocellular cancer cell proliferation, cycle and ferroptosis through POLE2
GINS4 silencing suppressed proliferation and cycle while promoted ferroptosis in HCC cells by regulating PI3K/AKT signaling via binding to POLE2.
Authors
- Congyu Wang (ORCID: https://orcid.org/0000-0002-9481-6822)
- Rui Song
- Heqiang Liao (ORCID: https://orcid.org/0009-0008-4794-2827)
- Jiarui Yao (ORCID: https://orcid.org/0000-0002-9835-395X)
- Xiangrui Zeng (ORCID: https://orcid.org/0000-0002-8589-4474)
- Zheng Zhang (ORCID: https://orcid.org/0009-0003-2498-9693)
- Zhe Xu (ORCID: https://orcid.org/0000-0002-9705-8924)
- Meng Yuan (ORCID: https://orcid.org/0000-0003-0087-6152)
- Huaicheng Yang (ORCID: https://orcid.org/0009-0004-3028-0880)
Institutions
- Anhui University of Science and Technology (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Cellular Signalling
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1016/j.cellsig.2025.111742
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56