Gold nanoparticles enhanced color stability in sweat glucose wearable colorimetric sensor based on automated microfluidic chip

Abstract This study presents a wearable colorimetric sensor based on microfluidic chips for a non-invasive, in situ analysis of epidermal sweat. The design includes a simple microfluidic chip made from PDMS with air venting, which enables an automatic collection of sweat into the reaction chamber. Within this chamber, a glass fiber-based electrode holds the reactive biochemicals. Both the microfluidic chip and the glass fiber electrode are treated with cold plasma to enhance the sensor’s sensitivity and stability during the operation. Additionally, we have developed an in-house website for real-time sensor signal analysis. The potential applications of this system are substantial due to its simple structure, convenient design, and ease of use.