Relationship of haptoglobin phenotype and levels with sight-threatening diabetic retinopathy in type 2 diabetes: A Fenofibrate Intervention and Event Lowering in diabetes (FIELD) substudy

Regarding STDR, fenofibrate benefit is greatest in type 2 diabetes patients with the lowest baseline HP levels, which may reflect patients more susceptible to oxidative retinal injury. All HP phenotypes benefit from fenofibrate.

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Publication Details

Journal
Diabetes Research and Clinical Practice
Published
2025-03-11
DOI
https://doi.org/10.1016/j.diabres.2025.112080
Citations
1
Primary Topic
Hemoglobin structure and function
Type
article
Field-Weighted Citation Impact
1.15
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article

Relationship of haptoglobin phenotype and levels with sight-threatening diabetic retinopathy in type 2 diabetes: A Fenofibrate Intervention and Event Lowering in diabetes (FIELD) substudy

ANTHONY C. KEECH, Andrzej S. Januszewski, Rachel O’Connell, Habib Francis et al.
1 citations
Diabetes Research and Clinical Practice
Hemoglobin structure and function
1.15
article

Relationship of haptoglobin phenotype and levels with sight-threatening diabetic retinopathy in type 2 diabetes: A Fenofibrate Intervention and Event Lowering in diabetes (FIELD) substudy

ANTHONY C. KEECH, Andrzej S. Januszewski, Rachel O’Connell, Habib Francis, Peter G. Colman, Kwok Leung Ong, DAVID R. SULLIVAN, Alicia J. Jenkins, Russell Scott, Abubakar Mangani, Liping Li
article en
1 citations

Abstract

Regarding STDR, fenofibrate benefit is greatest in type 2 diabetes patients with the lowest baseline HP levels, which may reflect patients more susceptible to oxidative retinal injury. All HP phenotypes benefit from fenofibrate.

Diabetes Research and Clinical PracticeVol. 222
The University of Sydney (AU), The Royal Melbourne Hospital (AU), Baker Heart and Diabetes Institute (AU), Royal Prince Alfred Hospital (AU), The Heart Research Institute (AU), Christchurch Hospital (NZ), National Health and Medical Research Council (AU)
Openalex Percentile: Top 27%
Hemoglobin structure and function
1.15
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Relationship of haptoglobin phenotype and levels with sight-threatening diabetic retinopathy in type 2 diabetes: A Fenofibrate Intervention and Event Lowering in diabetes (FIELD) substudy — ANTHONY C. KEECH, Andrzej S. Januszewski, et al. · Diabetes Research and Clinical Practice (2025) | TGRS Research Map | TGRS