Hypofractionated radiotherapy (RT) combined with dihydroartemisinin (DHA): No synergistic effect observed in a preliminary animal study
Similar treatment efficacy is observed in the RT alone and concurrent DHA+RT group. No significant difference in tumor volume or weight or tumor progression inhibition is observed between the RT alone and concurrent DHA+RT groups, demonstrating that DHA might not provide synergistic effect with RT for the proposed hypofractionated radiation dose regimen.
Authors
- Yuenan Wang (ORCID: https://orcid.org/0000-0001-6280-6956)
- Haitao Xiao (ORCID: https://orcid.org/0000-0001-5951-4426)
- Sanjay Aneja (ORCID: https://orcid.org/0000-0001-5681-7528)
- Xiaodong Yang (ORCID: https://orcid.org/0000-0002-0973-2537)
- Fada Guan (ORCID: https://orcid.org/0000-0001-8477-7391)
Institutions
- Yale University (US)
- Peking University Shenzhen Hospital (CN)
- Shenzhen University Health Science Center (CN)
Publication Details
- Journal
- Precision Radiation Oncology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/pro6.70002
- Citations
- 1
- Primary Topic
- Cancer therapeutics and mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.81