Potential biomarkers develop for predicting the prognosis of patients with esophageal squamous cell carcinoma after optimized chemoradiotherapy using serum metabolomics
CCRT shows considerable therapeutic benefit in patients with ESCC, with observed reductions in glucose metabolism post-treatment. L-phenylalanine and lysine may serve as potential serum biomarkers to predict CCRT efficacy.
Authors
- Jie Yang (ORCID: https://orcid.org/0000-0001-6604-7811)
- Kuancan Liu (ORCID: https://orcid.org/0000-0002-2470-7479)
- Yunyun Zhu
- Xiaodong Qi (ORCID: https://orcid.org/0000-0001-8200-6630)
- Xiajun Zhang
- Yongpan Liu (ORCID: https://orcid.org/0000-0002-4892-2309)
- Yijian Zhou
- Yuxuan Wei (ORCID: https://orcid.org/0000-0003-3336-951X)
- Jialing Xie (ORCID: https://orcid.org/0009-0008-2233-0824)
- Jiaying Zhang
- Zhichao Fu (ORCID: https://orcid.org/0000-0003-0341-106X)
- Lijia Zhang (ORCID: https://orcid.org/0000-0002-5728-6586)
- Yuting Yue
- Bo Zhang (ORCID: https://orcid.org/0009-0006-6595-3744)
- Xiaolu An
Institutions
- Xiamen University (CN)
- Government of Jiangsu Province (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s12885-025-13866-x
- Citations
- 1
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- National Natural Science Foundation of China
- Science Fund for Distinguished Young Scholars of Fujian Province