Bioactives derived from Brazilian native flora with antimicrobial and anticancer activity
The ethanolic extract of T. obtusa demonstrated antioxidant activity, antiproliferative effects against the 786-0 cell line, and antibacterial activity against MRSA. The ethanolic extract of S. fluminensis leaves exhibited a fungicidal effect against C. glabrata. These findings may pave the way for more effective and safer treatments for managing oncological and infectious diseases.
Authors
- Daniele Cristina Vitorelli-Venancio (ORCID: https://orcid.org/0000-0003-4021-4639)
- Giovana Bicudo Gomes (ORCID: https://orcid.org/0000-0002-9557-0959)
- Ângela Kwiatkowski (ORCID: https://orcid.org/0000-0002-6288-3318)
- Renata Trentin Perdomo (ORCID: https://orcid.org/0000-0003-2747-7039)
- Amanda Rodrigues Ganassin (ORCID: https://orcid.org/0000-0002-2141-5307)
- Fabio Antonio Venancio (ORCID: https://orcid.org/0000-0002-7458-7057)
- João Víctor de Andrade dos Santos
- Rosemary Matias (ORCID: https://orcid.org/0000-0002-0154-1015)
- Marilene Rodrigues Chang (ORCID: https://orcid.org/0000-0003-3402-4740)
Institutions
- Universidade Federal de Mato Grosso do Sul (BR)
- Universidade Federal da Grande Dourados (BR)
- Instituto Federal de Educação, Ciência e Tecnologia de Mato Grosso (BR)
- Anhanguera-Uniderp University (BR)
- Solução Ambiental Assessoria e Consultoria (BR)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s12906-025-04787-0
- Citations
- 1
- Primary Topic
- Bioactive Compounds and Antitumor Agents
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Universidade Federal de Mato Grosso do Sul