It’s Here, It’s There, There’s Fungi Everywhere: A Case Series Utilizing Rezafungin for Invasive Candidiasis
Rezafungin is a long-acting echinocandin with broad coverage against Candida. Rezafungin has primarily been indicated for candidemia, with limited literature available on its use for infections outside of the bloodstream. Herein, three patient cases are presented from an academic medical center. Infectious processes presented include drug-resistant mucosal candidiasis, prosthetic joint infection, and candidemia involving Candida auris. In all three cases, patients received rezafungin. Clinical response was demonstrated in all patients as was tolerability of rezafungin. Together these cases provide further evidence for the use of rezafungin, including its use for treatment of invasive infections other than candidemia.
Authors
- Robert W. Bradsher
- Jacob M. Keck
- Alina Viteri
- Juan Carlos Rico
- Ryan K Dare (ORCID: https://orcid.org/0000-0001-9540-2683)
- Jennifer L. McDonald (ORCID: https://orcid.org/0000-0002-6546-1014)
- Megan Jenkins
- Luke Grisham
Institutions
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- Infectious Diseases and Therapy
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1007/s40121-025-01120-7
- Citations
- 5
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 6.98