Quantification of Hydrogen Peroxide in PVP and PVPVA Using 1H qNMR Spectroscopy

<sup>1</sup>H qNMR spectroscopy is a valuable tool for accurately quantifying peroxide levels in pharmaceutical excipients. The study emphasizes the need for regular monitoring of peroxide content to ensure the stability, quality, and safety of excipients and drug products. Accurate peroxide measurement can prevent oxidative degradation, preserving both the safety and efficacy of pharmaceutical formulations.

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Publication Details

Journal
Polymers
Published
2025-03-11
DOI
https://doi.org/10.3390/polym17060739
Citations
3
Primary Topic
Spectroscopy and Chemometric Analyses
Type
article
Field-Weighted Citation Impact
2.26
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article

Quantification of Hydrogen Peroxide in PVP and PVPVA Using 1H qNMR Spectroscopy

Bernd Werner, Isha Saraf, Amrit Paudel, Varun Kushwah et al.
3 citations
Polymers
Spectroscopy and Chemometric Analyses
2.26
article

Quantification of Hydrogen Peroxide in PVP and PVPVA Using 1H qNMR Spectroscopy

Bernd Werner, Isha Saraf, Amrit Paudel, Varun Kushwah, Klaus Zangger
article en
3 citations

Abstract

<sup>1</sup>H qNMR spectroscopy is a valuable tool for accurately quantifying peroxide levels in pharmaceutical excipients. The study emphasizes the need for regular monitoring of peroxide content to ensure the stability, quality, and safety of excipients and drug products. Accurate peroxide measurement can prevent oxidative degradation, preserving both the safety and efficacy of pharmaceutical formulations.

PolymersVol. 17(6)
University of Graz (AT), Graz University of Technology (AT), Research Center Pharmaceutical Engineering (Austria) (AT)
Openalex Percentile: Top 14%
Spectroscopy and Chemometric Analyses
2.26
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