Exosomatic miR‐1246 Promotes Hepatocellular Carcinoma Progression via FSTL5 and ERK/p38 MAPK Pathway
In conclusion, tumor-derived miR-1246 enters hepatocellular carcinoma cells in the form of exosomes and promotes cancer cell invasion, EMT, and migration. The potential mechanism of miR-1246 is potentially relevant to the targeted gene FSTL5 as well as the ERK/p38 signaling.
Authors
- Wenju Chen
- Yingjie Dai
- Chunling Zhang (ORCID: https://orcid.org/0000-0002-8981-3184)
- Yichao Wang (ORCID: https://orcid.org/0009-0008-6627-350X)
- Wan‐hong Gu
Institutions
- Taizhou Central Hospital (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Journal of Biochemical and Molecular Toxicology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/jbt.70148
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42