Cerebral Edema Progression and Outcomes in Large Infarct Patients Undergoing Endovascular Thrombectomy

In patients with large infarct cores, EVT was associated with an early increased mass effect compared with MM, potentially mediating poorer functional outcomes. Despite the evident overall benefits from thrombectomy, accurate prediction and effective anti-edema interventions for the early mass effect post-EVT may further improve outcomes. The complex relationship between NWU and cerebral edema progression warrants further investigation. ANN NEUROL 2025;98:258-269.

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Publication Details

Journal
Annals of Neurology
Published
2025-03-11
DOI
https://doi.org/10.1002/ana.27235
Citations
8
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
10.83

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article

Cerebral Edema Progression and Outcomes in Large Infarct Patients Undergoing Endovascular Thrombectomy

Zhongrong Miao, Bernard Yan, Ximing Nie, Lina Zheng et al.
8 citations
Annals of Neurology
Acute Ischemic Stroke Management
10.83
article

Cerebral Edema Progression and Outcomes in Large Infarct Patients Undergoing Endovascular Thrombectomy

Zhongrong Miao, Bernard Yan, Ximing Nie, Lina Zheng, Xiaochuan Huo, Felix Ng, Yongle Wang, Yuesong Pan, Mengxing Wang, Liping Liu, Zan Wang, Sibo Liu, Jinjie Liu, Yuying Wang, Stephen M. Davis
article en
8 citations

Abstract

In patients with large infarct cores, EVT was associated with an early increased mass effect compared with MM, potentially mediating poorer functional outcomes. Despite the evident overall benefits from thrombectomy, accurate prediction and effective anti-edema interventions for the early mass effect post-EVT may further improve outcomes. The complex relationship between NWU and cerebral edema progression warrants further investigation. ANN NEUROL 2025;98:258-269.

Annals of NeurologyVol. 98(2)
The Royal Melbourne Hospital (AU), The University of Melbourne (AU), Shanxi Medical University (CN), Capital Medical University (CN), Dalian University of Technology (CN), Beijing Tian Tan Hospital (CN), National Clinical Research Center for Digestive Diseases (CN), Dalian Municipal Central Hospital (CN), Beijing Anzhen Hospital (CN), First Hospital of Shanxi Medical University (CN), Austin Health (AU), University of Science and Technology Beijing (CN), Tsinghua University (CN)
National Natural Science Foundation of China
No poverty
Openalex Percentile: Top 2%
Acute Ischemic Stroke Management
10.83
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