Flow-cytometric MRD detection in pediatric T-ALL: a multicenter AIEOP-BFM consensus-based guided standardized approach
Our work shows that standardized operating procedures together with guided analysis are applicable in a great majority of T-ALL cases. Further improvement of MRD detection is needed, as in some cases an individualized analytical approach is still required due to the challenging nature of the T-ALL phenotype.
Authors
- Helly Vernitsky (ORCID: https://orcid.org/0000-0001-5891-222X)
- Angela Schumich
- Tamar Feuerstein
- Pamela Scarparo
- Daniela Kužílková (ORCID: https://orcid.org/0000-0001-8086-9790)
- Oscar Maglia
- Ondřej Hrušák (ORCID: https://orcid.org/0000-0002-7611-1335)
- Barbara Buldini (ORCID: https://orcid.org/0000-0001-7285-2390)
- Margarita Maurer‐Granofszky (ORCID: https://orcid.org/0000-0003-3519-9972)
- Giovanni Faggin (ORCID: https://orcid.org/0000-0002-5443-5638)
- Michael Dworzak (ORCID: https://orcid.org/0000-0002-8175-1097)
- Zuzana Šestáková (ORCID: https://orcid.org/0000-0003-3229-0404)
- Michaela Nováková (ORCID: https://orcid.org/0000-0003-2964-5956)
- Saskia Kohlscheen
- Monika Brüggemann (ORCID: https://orcid.org/0000-0001-5514-5010)
- Simona Sala (ORCID: https://orcid.org/0000-0001-6357-0375)
- Elena Varotto (ORCID: https://orcid.org/0000-0003-2141-9786)
- Giuseppe Gaipa (ORCID: https://orcid.org/0000-0002-1006-5946)
- Peter Švec (ORCID: https://orcid.org/0000-0002-7647-2253)
- Tomáš Kalina (ORCID: https://orcid.org/0000-0003-4475-2872)
Institutions
- University of Padua (IT)
- Charles University (CZ)
- Sheba Medical Center (IL)
- Christian-Albrechts-Universität zu Kiel (DE)
- National Institute of Cardiovascular Diseases (SK)
- University Hospital in Motol (CZ)
- Schneider Children's Medical Center (IL)
- St Anna Children's Hospital (AT)
- Città della Speranza Foundation (IT)
- St. Anna Children's Cancer Research Institute
- Medical University of Vienna (AT)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1515/cclm-2024-1503
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Ministero della Salute
- Ministerstvo Zdravotnictví Ceské Republiky