A survey on measurement and reporting of total testosterone, sex hormone-binding globulin and free testosterone in clinical laboratories in Europe
Our survey highlights significant inter-laboratory variability for the assessment of androgen status in men, implying non-commutability of clinical test results between different centers. In addition, we observed poor adherence to pre-analytical recommendations. These findings advocate for continued harmonization efforts of measurement procedures for SHBG and total/free T.
Authors
- Bruno Lapauw (ORCID: https://orcid.org/0000-0002-1584-4965)
- Nick Narinx (ORCID: https://orcid.org/0000-0002-7342-8724)
- Jaak Billen (ORCID: https://orcid.org/0000-0003-4852-4340)
- Tom Fiers (ORCID: https://orcid.org/0000-0003-1398-5489)
- Joeri Walravens (ORCID: https://orcid.org/0000-0001-5159-3238)
- Brigitte Decallonne (ORCID: https://orcid.org/0000-0003-4153-4757)
- Frank Claessens (ORCID: https://orcid.org/0000-0002-8676-7709)
- Leen Antonio (ORCID: https://orcid.org/0000-0002-1079-2860)
- Vera Sommers (ORCID: https://orcid.org/0000-0003-2289-9179)
- Dirk Vanderschueren (ORCID: https://orcid.org/0000-0003-1395-0104)
- Pieter Vermeersch (ORCID: https://orcid.org/0000-0001-7076-061X)
- Katleen Van Uytfanghe (ORCID: https://orcid.org/0000-0001-8195-150X)
- Karel David (ORCID: https://orcid.org/0000-0001-6050-6677)
- Jennifer Afrakoma Nyamaah (ORCID: https://orcid.org/0009-0002-4787-3637)
Institutions
- Ghent University Hospital (BE)
- Ghent University (BE)
- KU Leuven (BE)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1515/cclm-2024-1237
- Citations
- 5
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 6.47
Funders
- Fonds Wetenschappelijk Onderzoek