In vivo Terahertz Sensing of Skin Cancer Patients

The first in vivo study of skin cancer patients using a handheld terahertz (THz) scanner is conducted in a clinical environment. By devising a patient‐ normalized response function, it has been able to obtain clear difference between the THz measurements of healthy and cancerous skin. However, due to the variety of lesions and skin locations measured, the contrast is not consistent between patients and more work is needed to understand the contrast mechanism. The transient behavior of the THz response is also isolated during a measurement, showing that the surface of the skin compresses during the in vivo measurement. Understanding this response has enabled the development of the patient‐invariant parameter that is formulated in this work and may potentially serve to simplify measurement protocols in future studies.

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Publication Details

Journal
Advanced Photonics Research
Published
2025-03-02
DOI
https://doi.org/10.1002/adpr.202400195
Citations
4
Primary Topic
Terahertz technology and applications
Type
article
Field-Weighted Citation Impact
2.92

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article

In vivo Terahertz Sensing of Skin Cancer Patients

Emma Pickwell‐MacPherson, Jacob J. Young, Joseph Hardwicke, Brendan Page et al.
4 citations
Advanced Photonics Research
Terahertz technology and applications
2.92
article

In vivo Terahertz Sensing of Skin Cancer Patients

Emma Pickwell‐MacPherson, Jacob J. Young, Joseph Hardwicke, Brendan Page, Arturo I. Hernandez‐Serrano
article en
4 citations

Abstract

The first in vivo study of skin cancer patients using a handheld terahertz (THz) scanner is conducted in a clinical environment. By devising a patient‐ normalized response function, it has been able to obtain clear difference between the THz measurements of healthy and cancerous skin. However, due to the variety of lesions and skin locations measured, the contrast is not consistent between patients and more work is needed to understand the contrast mechanism. The transient behavior of the THz response is also isolated during a measurement, showing that the surface of the skin compresses during the in vivo measurement. Understanding this response has enabled the development of the patient‐invariant parameter that is formulated in this work and may potentially serve to simplify measurement protocols in future studies.

Advanced Photonics ResearchVol. 6(6)
University Hospital Coventry (GB), University of Warwick (GB)
Cancer Research UK, Royal Society, Engineering and Physical Sciences Research Council
Openalex Percentile: Top 10%
Terahertz technology and applications
2.92
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