Investigation of HO-1 Regulation of Liver Fibrosis Related to Nonalcoholic Fatty Liver Disease Through the SIRT1/TGF-ß/Smad3 Pathway
HO-1 inhibits the activation of the TGF-ß/Smad3 pathway in NAFLD-related liver fibrosis through SIRT1. These findings provide insights into new therapeutic strategies for treating NAFLD-associated liver fibrosis.
Authors
- Mengjiao Sun
- Congyue Zhang (ORCID: https://orcid.org/0000-0002-7498-6576)
- Jiawei Cui (ORCID: https://orcid.org/0000-0002-3547-9563)
- Yimin Mao (ORCID: https://orcid.org/0000-0002-2928-3425)
- Yuemin Nan (ORCID: https://orcid.org/0000-0003-4192-099X)
- Jiaming Zhang (ORCID: https://orcid.org/0009-0006-7842-9693)
- Xiaoqing Wu
- Yue Shi (ORCID: https://orcid.org/0009-0003-3287-2612)
- Zhenhai Lin
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2025-03-12
- DOI
- https://doi.org/10.14218/jcth.2024.00481
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00