The causal relationships between inflammatory cytokines, blood metabolites, and thyroid cancer: a two-step Mendelian randomization analysis
This study identified some inflammatory cytokines and blood metabolites associated with thyroid cancer risk and revealed the mediating role of specific blood metabolites between TNFSF14 and thyroid cancer, highlighting the critical role of inflammatory and metabolic pathways in the pathogenesis of thyroid cancer.
Authors
- Yuxiao Sun (ORCID: https://orcid.org/0009-0003-6817-7865)
- W. Liu (ORCID: https://orcid.org/0009-0004-2893-9009)
- Detao Yin (ORCID: https://orcid.org/0000-0002-4349-6857)
- Yifei Zhang (ORCID: https://orcid.org/0000-0003-3637-6010)
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-03-12
- DOI
- https://doi.org/10.1007/s12672-025-02029-w
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04