Clinical and radiographic evaluation of bone graft after apicoectomy using porcine-derived collagenous block type xenograft

Purpose: This study examined the clinical and radiographic outcomes of using a porcine-derived collagenous block-type xenograft in periapical bone regeneration after apicoectomy. Materials and Methods:A retrospective analysis was conducted on 15 patients (nine males, six females; mean age: 42.612.3years) who underwent an apicoectomy with subsequent bone grafting using porcine-derived collagenous block type xenograft (LegoGraft, Purgo Biologics, Seongnam, Republic of Korea) between October 2021 and March 2023.Periapical radiographs were taken preoperatively, immediately postoperatively, and at three and 12 months post-surgery.The bone density was assessed by measuring the grayscale values in the region of interest and comparing them with the adjacent normal bone. Results:No complications, such as infection, inflammation, or wound dehiscence, were observed during the mean follow-up period of 17.18.3months.The mean grayscale values increased significantly from 108.5845.35preoperatively to 139.3733.68immediately postoperatively (P0.001), with stabilization at 138.2028.09at 12 months (P=0.024).No significant differences in bone density were observed between genders or between the anterior and posterior teeth at any time. Conclusions:The porcine-derived collagenous block-type xenograft showed stable and predictable bone regeneration after the apicoectomy, with remodeling patterns similar to the surrounding natural bone.These findings suggest that this graft material is a reliable option for periapical bone regeneration.(