Coronary Arteries Involvement in Giant Cell Arteritis Diagnosis Using 2-[18F]FDG-PET/CT

Coronary artery involvement in giant cell arteritis (GCA) is rare but can lead to severe complications, including myocardial infarction and death. We present unique 2-[ 18 F]fluorodeoxyglucose positron emission tomography/computed tomography (2-[ 18 F]FDG-PET/CT) findings in a 91-year-old woman with GCA. In addition to typical aortic and supra-aortic involvement, this scan revealed intense FDG uptake in the coronary arteries, including the left main trunk, left anterior descending, circumflex, and right coronary arteries. This inflammatory pattern was consistent with GCA, with no signs of atherosclerosis on coronary CT angiography. Early identification of coronary inflammation enabled timely immunosuppressive therapy, potentially preventing fatal outcomes.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-03-11
DOI
https://doi.org/10.1097/rlu.0000000000005807
Citations
2
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
3.04
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article

Coronary Arteries Involvement in Giant Cell Arteritis Diagnosis Using 2-[18F]FDG-PET/CT

Françoise Kraeber‐Bodéré, Julien Kunsch, Bastien Jamet, Olivier Espitia et al.
2 citations
Clinical Nuclear Medicine
Vasculitis and related conditions
3.04
article

Coronary Arteries Involvement in Giant Cell Arteritis Diagnosis Using 2-[18F]FDG-PET/CT

Françoise Kraeber‐Bodéré, Julien Kunsch, Bastien Jamet, Olivier Espitia, Marine Eustache
article en
2 citations

Abstract

Coronary artery involvement in giant cell arteritis (GCA) is rare but can lead to severe complications, including myocardial infarction and death. We present unique 2-[ 18 F]fluorodeoxyglucose positron emission tomography/computed tomography (2-[ 18 F]FDG-PET/CT) findings in a 91-year-old woman with GCA. In addition to typical aortic and supra-aortic involvement, this scan revealed intense FDG uptake in the coronary arteries, including the left main trunk, left anterior descending, circumflex, and right coronary arteries. This inflammatory pattern was consistent with GCA, with no signs of atherosclerosis on coronary CT angiography. Early identification of coronary inflammation enabled timely immunosuppressive therapy, potentially preventing fatal outcomes.

Clinical Nuclear MedicineVol. 50(6)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Centre Hospitalier Régional et Universitaire de Nancy (FR), Institut du Thorax (FR), Nantes Université (FR)
Good health and well-being
Openalex Percentile: Top 11%
Vasculitis and related conditions
3.04
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