Case Report: Ofatumumab treatment for concomitant multiple sclerosis and idiopathic thrombocytopenic purpura

Herein, we report our experience with a novel case of MS concomitant with ITP that was safely treated with ofatumumab. Considering the pharmacological similarities of ofatumumab to rituximab (a second-line treatment for ITP), anti-CD20 monoclonal antibodies such as ofatumumab could be a promising treatment option for cases of MS concomitant with ITP.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-03-11
DOI
https://doi.org/10.3389/fimmu.2025.1515776
Primary Topic
Platelet Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Case Report: Ofatumumab treatment for concomitant multiple sclerosis and idiopathic thrombocytopenic purpura

Yuki Yokota, Hideto Nakajima, Makoto Hara
Frontiers in Immunology
Platelet Disorders and Treatments
article

Case Report: Ofatumumab treatment for concomitant multiple sclerosis and idiopathic thrombocytopenic purpura

Yuki Yokota, Hideto Nakajima, Makoto Hara
article en

Abstract

Herein, we report our experience with a novel case of MS concomitant with ITP that was safely treated with ofatumumab. Considering the pharmacological similarities of ofatumumab to rituximab (a second-line treatment for ITP), anti-CD20 monoclonal antibodies such as ofatumumab could be a promising treatment option for cases of MS concomitant with ITP.

Frontiers in ImmunologyVol. 16
Nihon University (JP)
Ministry of Health, Labour and Welfare, Japan Society for the Promotion of Science
Good health and well-being
Openalex Percentile: Top 94%
Platelet Disorders and Treatments
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