Methylation of the telomerase gene promoter region in umbilical cord blood of patients with gestational diabetes mellitus is associated with decreased telomerase expression levels and shortened telomere length
This study revealed that GDM may induce decreased TE expression by increasing the methylation levels of TE genes promoter region, thereby reducing the TL.
Authors
- Mingming Zheng (ORCID: https://orcid.org/0000-0003-0611-5581)
- Shuhua Liu (ORCID: https://orcid.org/0000-0002-5133-329X)
- Xianxia Chen
- Yan Cheng (ORCID: https://orcid.org/0000-0002-0919-672X)
- Liping Xu (ORCID: https://orcid.org/0000-0003-4434-1213)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-6286-6227)
- Dehong Liu (ORCID: https://orcid.org/0000-0003-1934-4009)
Institutions
- Anhui Medical University (CN)
- Anhui Provincial Children's Hospital (CN)
- Hefei Infectious Disease Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-03-11
- DOI
- https://doi.org/10.3389/fendo.2025.1502329
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00