Alteration of prefrontal functional connectivity in preclinical Alzheimer's disease: an fNIRS study
The initial increase and subsequent reduction of interhemispheric functional connectivity in the preclinical AD group across task repetitions suggests that task-related prefrontal network alterations may occur during the preclinical phase of AD and shows its potential as a biomarker for screening preclinical AD.
Authors
- Jeonghwan Gwak (ORCID: https://orcid.org/0000-0002-6237-0141)
- Jae Gwan Kim (ORCID: https://orcid.org/0000-0002-1010-7712)
- Byeong C. Kim (ORCID: https://orcid.org/0000-0001-6827-6730)
- Kun Ho Lee (ORCID: https://orcid.org/0000-0003-4144-8162)
- Jang Jae Lee (ORCID: https://orcid.org/0000-0001-8787-9940)
- Kyu Yeong Choi (ORCID: https://orcid.org/0000-0003-1872-6953)
- Minhee Kim (ORCID: https://orcid.org/0000-0001-8468-5470)
Institutions
- Korea National University of Transportation (KR)
- Chosun University (KR)
- Gwangju Institute of Science and Technology (KR)
- Chonnam National University Hospital (KR)
- Korea Brain Research Institute (KR)
- Gwangju University (KR)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-03-11
- DOI
- https://doi.org/10.3389/fnagi.2025.1507180
- Citations
- 3
- Primary Topic
- Optical Imaging and Spectroscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 4.08