Response surface-based media optimization for astaxanthin production in Corynebacterium glutamicum
By increasing the concentration of iron and decreasing that of manganese especially, it was possible to increase astaxanthin titers from 7.9 mg L<sup>-1</sup>-39.6 mg L<sup>-1</sup> in a micro cultivation system and from 62 mg L<sup>-1</sup>-176 mg L<sup>-1</sup> in a fed-batch fermentation.
Authors
- Florian Meyer (ORCID: https://orcid.org/0000-0002-8349-1153)
- Volker F. Wendisch (ORCID: https://orcid.org/0000-0003-3473-0012)
- Nadja A. Henke (ORCID: https://orcid.org/0000-0002-1304-6310)
- Ina Schmitt (ORCID: https://orcid.org/0009-0002-3418-8796)
Institutions
- Bielefeld University (DE)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-03-11
- DOI
- https://doi.org/10.3389/fbioe.2025.1516522
- Citations
- 6
- Primary Topic
- Algal biology and biofuel production
- Type
- article
- Field-Weighted Citation Impact
- 2.18
Funders
- Bundesministerium für Bildung und Forschung
- European Regional Development Fund