Non-tuberculous mycobacteria isolates from patients with chronic pulmonary disease and no epidemiological relationship show sequence clusters through whole-genome sequencing
<i>M. intracellulare</i> subsp. <i>chimaera</i> and <i>M. intracellulare</i> subsp. <i>intracellulare</i> form clusters of very closely related isolates from patients with no epidemiological relationship. This absence of an epidemiological relationship indicated that the infections were likely acquired from common sources rather than through direct transmission between patients. The use of three methodologies is an adequate strategy for an in-depth study of the relationship between isolates of very closely related species and subspecies.
Authors
- Maria Antònia Busquets (ORCID: https://orcid.org/0000-0002-6232-9886)
- Joan Estelrich (ORCID: https://orcid.org/0000-0002-1373-3671)
- Montserrat Garrigó (ORCID: https://orcid.org/0000-0003-4431-4733)
- Diego Martínez (ORCID: https://orcid.org/0000-0001-8651-582X)
- Mariana Fernández-Pittol (ORCID: https://orcid.org/0000-0002-1685-7127)
- Griselda Tudó (ORCID: https://orcid.org/0000-0002-9241-7051)
- Lorena San Nicolás
- Ferrán Navarro (ORCID: https://orcid.org/0000-0002-4302-2838)
- Elena Portell-Buj
- Marc Rubio (ORCID: https://orcid.org/0000-0002-4811-0642)
- Sara Batista
- Julian González-Martín (ORCID: https://orcid.org/0000-0001-7248-6706)
Institutions
- Universitat Autònoma de Barcelona (ES)
- Instituto de Salud Carlos III (ES)
- Hospital de Sant Pau (ES)
- Departament de Salut (ES)
- Hospital Clínic de Barcelona (ES)
- Barcelona Institute for Global Health (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Institut de Nanociència i Nanotecnologia de la Universitat de Barcelona
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-03-11
- DOI
- https://doi.org/10.3389/fmicb.2025.1549030
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundació la Marató de TV3
- Generalitat de Catalunya
- Ministerio de Ciencia e Innovación
- Sociedad Española de Neumología y Cirugía Torácica
- Instituto de Salud Carlos III
- Departament d'Universitats, Recerca i Societat de la Informació
- European Regional Development Fund