Cancer immunotherapy by silencing transcription factor c-Rel using peptide-based nanoparticles
Our data indicates that peptide-based nanoparticles can be successfully utilized to target the myeloid immune checkpoint c-Rel for the treatment of cancer.
Authors
- Zibin Tan (ORCID: https://orcid.org/0000-0003-0744-0693)
- Yuxuan Zhu (ORCID: https://orcid.org/0000-0002-5234-8506)
- Lintao Cai (ORCID: https://orcid.org/0000-0002-2461-6390)
- Shuyao Lang (ORCID: https://orcid.org/0000-0003-1800-7641)
- Ruijing Liang (ORCID: https://orcid.org/0000-0003-3248-2780)
- Youhai H. Chen (ORCID: https://orcid.org/0000-0002-9695-6757)
- Ping Li (ORCID: https://orcid.org/0000-0003-2843-4460)
- Fan Pan
- Jian Ren
- Yu Zhang (ORCID: https://orcid.org/0009-0009-6733-6338)
Institutions
- Shenzhen University (CN)
- Chinese Academy of Sciences (CN)
- Shenzhen Institutes of Advanced Technology (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-11
- DOI
- https://doi.org/10.3389/fimmu.2025.1554496
- Citations
- 2
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.59