Adaptive attenuation of virulence mediated by Wzc mutation in ST11-KL47 Carbapenem-resistant Klebsiella pneumonia

These findings demonstrate that the Wzc-induced HMV attenuates ST11-KL47 CRKp virulence by modifying the exopolysaccharide composition and physical distribution.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2025-03-11
DOI
https://doi.org/10.3389/fcimb.2025.1561631
Citations
6
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
3.55
Controls
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article

Adaptive attenuation of virulence mediated by Wzc mutation in ST11-KL47 Carbapenem-resistant Klebsiella pneumonia

Yufeng Dai, Ling Guo, Qiang Zhao, Kun Ye et al.
6 citations
Frontiers in Cellular and Infection Microbiology
Antibiotic Resistance in Bacteria
3.55
article

Adaptive attenuation of virulence mediated by Wzc mutation in ST11-KL47 Carbapenem-resistant Klebsiella pneumonia

Yufeng Dai, Ling Guo, Qiang Zhao, Kun Ye, Huanhuan Yan, Lifeng Wang, Wenwen Li, Na Guo, Jiyong Yang
article en
6 citations

Abstract

These findings demonstrate that the Wzc-induced HMV attenuates ST11-KL47 CRKp virulence by modifying the exopolysaccharide composition and physical distribution.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Chinese People's Liberation Army (CN)
Openalex Percentile: Top 7%
Antibiotic Resistance in Bacteria
3.55
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