Mathematical Analysis of Vaccination and Immunity Dynamics in Polio Eradication Efforts in Nigeria

Polio eradication efforts in Nigeria have seen significant progress, marked by an ongoing commitment to vaccination programs and public health initiatives. This article explores the mathematical modeling of polio transmission dynamics, with a focus on the impact of vaccination and immunity on disease control. A system of differential equations is developed to represent the spread of polio and the role of vaccination strategies. The model accounts for susceptible, vaccinated, infectious, and recovered populations, as well as the waning of vaccine-induced immunity. The analysis provides insights into the threshold conditions required for polio eradication and the implications of vaccination coverage, immunity waning, and population dynamics. The results suggest that achieving and sustaining high vaccination coverage remains crucial for eliminating polio, alongside addressing vaccine hesitancy and improving immunization strategies.

Authors

Publication Details

Journal
International Journal of Advanced Multidisciplinary Research and Studies
Published
2025-03-05
DOI
https://doi.org/10.62225/2583049x.2025.5.2.3825
Citations
1
Primary Topic
Viral Infections and Immunology Research
Type
article
Field-Weighted Citation Impact
1.39
Controls
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article

Mathematical Analysis of Vaccination and Immunity Dynamics in Polio Eradication Efforts in Nigeria

Abdulrahman-Odumu Elizabeth O, Okedoye Akindele M
1 citations
International Journal of Advanced Multidisciplinary Research and Studies
Viral Infections and Immunology Research
1.39
article

Mathematical Analysis of Vaccination and Immunity Dynamics in Polio Eradication Efforts in Nigeria

Abdulrahman-Odumu Elizabeth O, Okedoye Akindele M
article en
1 citations

Abstract

Polio eradication efforts in Nigeria have seen significant progress, marked by an ongoing commitment to vaccination programs and public health initiatives. This article explores the mathematical modeling of polio transmission dynamics, with a focus on the impact of vaccination and immunity on disease control. A system of differential equations is developed to represent the spread of polio and the role of vaccination strategies. The model accounts for susceptible, vaccinated, infectious, and recovered populations, as well as the waning of vaccine-induced immunity. The analysis provides insights into the threshold conditions required for polio eradication and the implications of vaccination coverage, immunity waning, and population dynamics. The results suggest that achieving and sustaining high vaccination coverage remains crucial for eliminating polio, alongside addressing vaccine hesitancy and improving immunization strategies.

International Journal of Advanced Multidisciplinary Research and StudiesVol. 5(2)
Good health and well-being
Openalex Percentile: Top 22%
Viral Infections and Immunology Research
1.39
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Mathematical Analysis of Vaccination and Immunity Dynamics in Polio Eradication Efforts in Nigeria — Abdulrahman-Odumu Elizabeth O, Okedoye Akindele M · International Journal of Advanced Multidisciplinary Research and Studies (2025) | TGRS Research Map | TGRS