PINCH-1 promotes tumor growth and metastasis by enhancing DRP1-mediated mitochondrial fission in head and neck squamous cell carcinoma

PINCH-1 plays a critical oncogenic role in HNSCC by enhancing DRP1-mediated mitochondrial fission, which may serve as a novel therapeutic target for HNSCC.

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Publication Details

Journal
Cancer Biology & Therapy
Published
2025-03-11
DOI
https://doi.org/10.1080/15384047.2025.2477365
Citations
5
Primary Topic
Mitochondrial Function and Pathology
Type
article
Field-Weighted Citation Impact
4.03
Controls
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article

PINCH-1 promotes tumor growth and metastasis by enhancing DRP1-mediated mitochondrial fission in head and neck squamous cell carcinoma

Hao Song, Ting Yuan, Ruxian Tian, Lei Dong et al.
5 citations
Cancer Biology & Therapy
Mitochondrial Function and Pathology
4.03
article

PINCH-1 promotes tumor growth and metastasis by enhancing DRP1-mediated mitochondrial fission in head and neck squamous cell carcinoma

Hao Song, Ting Yuan, Ruxian Tian, Lei Dong, Jiahui Liu, Jiaxuan Li, Yaqi Wang, Yumei Li
article en
5 citations

Abstract

PINCH-1 plays a critical oncogenic role in HNSCC by enhancing DRP1-mediated mitochondrial fission, which may serve as a novel therapeutic target for HNSCC.

Cancer Biology & TherapyVol. 26(1)
Qingdao University (CN), Yuhuangding Hospital (CN)
Openalex Percentile: Top 7%
Mitochondrial Function and Pathology
4.03
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