IVF success rates in individuals accessing preimplantation genetic testing for monogenic conditions (PGT-M): a single centre retrospective cohort study of 572 IVF cycles
Individuals accessing preimplantation genetic testing for monogenic conditions have higher clinical pregnancy and live birth rates than couples accessing in vitro fertilization for other indications such as subfertility. These findings confirm that preimplantation genetic testing is an effective reproductive option for Australian carrier individuals.
Authors
- Sarah J. Lewis (ORCID: https://orcid.org/0000-0003-4311-6890)
- Tristan Hardy (ORCID: https://orcid.org/0000-0002-5878-0340)
- Lisa Hui (ORCID: https://orcid.org/0000-0002-9720-3562)
- Alice Poulton (ORCID: https://orcid.org/0000-0003-3506-9035)
- Melody A. Menezes (ORCID: https://orcid.org/0000-0003-3854-0224)
Institutions
- The University of Melbourne (AU)
- Mercy Hospital for Women (AU)
- Northern Hospital (AU)
- Victorian Clinical Genetics Services (AU)
- Monash IVF (AU)
- Murdoch Children's Research Institute (AU)
Publication Details
- Journal
- Journal of Assisted Reproduction and Genetics
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1007/s10815-025-03416-6
- Citations
- 4
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 13.98
Funders
- Murdoch Children's Research Institute
- University of Melbourne
- National Health and Medical Research Council