Causal effects and mediating pathways of metabolic dysfunction-associated fatty liver disease on novel subtypes of adult-onset diabetes: A two-step Mendelian randomization study
This study underscores the causal relationship between MAFLD and specific diabetes subtypes, highlighting the importance of integrated management of liver lipid metabolism, abdominal obesity, and blood glucose regulation. These findings support personalized intervention strategies.
Authors
- Rongrong Li (ORCID: https://orcid.org/0000-0003-1176-0702)
- Ting Wang (ORCID: https://orcid.org/0000-0001-7414-5390)
- Yawei Fan (ORCID: https://orcid.org/0009-0006-0618-8499)
- Yan Guan
- Ye Tian (ORCID: https://orcid.org/0000-0001-6080-1289)
- Hongping Luo (ORCID: https://orcid.org/0000-0003-2205-6219)
Institutions
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Nutrition Metabolism and Cardiovascular Diseases
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1016/j.numecd.2025.103976
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35