Platycodin D Enhances Glioma Sensitivity to Temozolomide by Inhibition of the Wnt/β-Catenin Pathway
PD augmented glioma cell sensitivity to TMZ by modulating Wnt/β-catenin pathway. Our findings demonstrate the potential of PD as an innovative therapeutic agent to enhance glioma treatment, especially in TMZ-resistant gliomas.
Authors
- Chao Qian (ORCID: https://orcid.org/0000-0002-5869-9227)
- Haima Li
- Xuelian Wang (ORCID: https://orcid.org/0000-0003-0671-5958)
- Jia Ouyang (ORCID: https://orcid.org/0000-0002-7601-5773)
Institutions
- Peking University (CN)
- Peking University People's Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2147/dddt.s503167
- Citations
- 2
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61