RBM10 deficiency promotes brain metastasis by modulating sphingolipid metabolism in a BBB model of EGFR mutant lung adenocarcinoma
This study offers insights into the potential mechanisms of brain metastasis in LUAD and suggests a possible therapeutic target for further investigation.
Authors
- Weitong Gao
- Ruqiong Wang
- Enguang Lin
- Bo Pan (ORCID: https://orcid.org/0000-0002-0984-2058)
- Lihua Shang (ORCID: https://orcid.org/0000-0001-6600-7959)
- Yan Jin (ORCID: https://orcid.org/0000-0002-2586-1152)
- Zihan Jing
- Bo An (ORCID: https://orcid.org/0000-0002-1031-3380)
- Huiting Hao
- Gang Xu (ORCID: https://orcid.org/0000-0001-6862-0546)
- Yajie Li (ORCID: https://orcid.org/0000-0002-4409-5203)
- Yan Yu (ORCID: https://orcid.org/0000-0001-5598-763X)
- Xingmei Ren
- Dexin Jia
Institutions
- Harbin Medical University (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s13046-025-03347-1
- Citations
- 3
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- National Natural Science Foundation of China