Application of various physiotherapeutic technologies for correction of involutionary changes in the skin

Objective: evaluation of the effectiveness of laser phoresis of the balm «Placentol 100 %”, transcranial magnetic therapy and oxygen barotherapy, used both as a single effect and in the mode of complex use, for the correction of involutional changes in the skin of the face in patients suffering from metabolic syndrome. Materials and methods. The study was conducted at the Clinic of Expert Cosmetology and Aesthetic Medicine «Love Clinic» with the participation of 120 women with involutional changes in the facial skin, suffering from metabolic syndrome. Using the method of simple fixed randomization, all patients were divided into 4 equal groups of 30 people. The first group (comparison group 1) received laserphoresis of the balm «Placentol 100 %”. The second group (comparison group 2) received a course of transcranial magnetic therapy using the «Amo-Atos» device with the «Headband» attachment. The third group (comparison group 3) received a course of oxygen barotherapy. The fourth group (main group) received a course of complex treatment, including laser phoresis of Placentol 100 % balm, transcranial magnetic therapy and oxygen barotherapy. Evaluation of clinical efficacy in the selected groups was based on the dynamics of the dermatological quality of life index; visual analogue scale of facial skin condition (VAS); international aesthetic improvement scale (GAIS), objective parameters of facial skin (hydration, elasticity, oiliness, skin pH), cutometry and corneometry. Additionally, the insulin resistance index, body mass index, atherogenicity coefficient, oxidative stress patterns and proinflammatory cytokines were determined. Results. A pronounced advantage of combined physiotherapy over the monofactorial use of therapeutic physical factors was established. It was shown that laserphoresis of Placentol 100 % balm had a greater effect on the clinical manifestations of involutional processes, transcranial magnetic therapy — on metabolic parameters, oxidative stress and inflammatory reactions, oxygen barotherapy — only on the lipid peroxidation system and systemic inflammation parameters. Analysis of the types of interaction of therapeutic physical factors in combined use made it possible to establish that 26 % of the variables used reflected the supra-additive (potentiating) nature of the implementation of the therapeutic effect of complex physiotherapy. Conclusion. An integrated approach to the correction of involutional changes in the facial skin in patients with metabolic syndrome allows for therapy taking into account the systemic mechanisms of comorbidity that determine the mutual additive nature of the clinical manifestations of the underlying disease and the pathological condition associated with it. The results of the study confirm the feasibility of developing complex methods of therapy in the field of dermatology and cosmetology based on physiotherapeutic technologies that are easy to use, accessible to the general population and have virtually no side effects.