Detection of NLRP3, ASC, and Caspase-1 in serum and cerebrospinal fluid of traumatic brain injury patients: implications for short-term prognosis
NLRP3, ASC, and Caspase-1 are promising biomarkers for evaluating TBI severity and predicting outcomes. Their dynamic monitoring may improve clinical management and in-form therapeutic strategies. Future research should validate these findings in larger cohorts and explore interventions targeting these inflammatory pathways.
Authors
- Jinhui Xu
- X.F. Liu
- Jilin Li (ORCID: https://orcid.org/0000-0003-3312-5478)
- Adilijiang Aihemaitiniyazi (ORCID: https://orcid.org/0009-0006-3305-2263)
- Hua Chen (ORCID: https://orcid.org/0000-0002-4172-5548)
- Kuo Ma
Institutions
- Fudan University (CN)
- Zhongshan Hospital (CN)
Publication Details
- Journal
- Acta Neurologica Belgica
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1007/s13760-025-02761-8
- Citations
- 2
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Bengbu Medical College