Investigation of the Effect of Empagliflozin on Cardiac Sympathetic and Parasympathetic Nerve Activity Analyzed From Heart Rate Variability Frequency in Japanese Patients With Type 2 Diabetes ― Results From the EMPYREAN Study ―
The effects of empagliflozin and sitagliptin on autonomic nerve activity did not differ significantly in patients with T2D.
Authors
- Nobuyuki Azuma
- Terumoto Fukuchi
- Mitsuaki Horigome
- Koji Oba (ORCID: https://orcid.org/0000-0001-5468-8988)
- Megumi Koshikawa
- Eiichiro Mawatari
- Koichiro Kuwahara (ORCID: https://orcid.org/0000-0003-2670-7170)
- Shinya Hiramitsu
- Koji Yoshie (ORCID: https://orcid.org/0000-0002-2378-2768)
- Masanori Nishino
- Izuru Masuda (ORCID: https://orcid.org/0000-0002-5665-9782)
- Masako Waki (ORCID: https://orcid.org/0000-0001-7721-7302)
- Toshiki Fukui
- Wataru Shoin
- Hirohiko Motoki (ORCID: https://orcid.org/0000-0002-5219-6856)
- Yoshito Inobe
- Hideki Chusho
- Tomoaki Mochidome (ORCID: https://orcid.org/0000-0002-3994-6130)
- Kazuya Yamamoto (ORCID: https://orcid.org/0000-0002-0611-6392)
- Takeshi Kimura (ORCID: https://orcid.org/0000-0003-1179-8903)
- Masako Nakano (ORCID: https://orcid.org/0000-0003-1025-2386)
- Sadao Nakajima
- Masatoshi Minamisawa
- Shinji Yasuno
Institutions
- Shinshu University (JP)
- Funai Electric (Japan) (JP)
- Kyoto University (JP)
- Alameda Hospital (US)
- Fukui Red Cross Hospital (JP)
- Ijinkai Takeda General Hospital (JP)
- Ikeda Municipal Hospital (JP)
- Saku Central Hospital (JP)
- Nagano Municipal Hospital (JP)
- Shizuoka City Hospital (JP)
- Azumi Hospital (JP)
- Fukui CardioVascular Center (JP)
- Matsumoto University (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Circulation Journal
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1253/circj.cj-24-0799
- Citations
- 1
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Eli Lilly and Company