CGREF1 facilitates the cell proliferation, migration and invasion of hepatocellular carcinoma cells via regulation of EIF3H/ Wnt/β-Catenin signaling axis

CGREF1 is upregulated in HCC and acted as an oncogene through the CGREF1/EIF3H/Wnt/β-Catenin signaling axis. These findings suggest that CGREF1 may emerge as a potential therapeutic target for HCC.

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Publication Details

Journal
BMC Cancer
Published
2025-03-11
DOI
https://doi.org/10.1186/s12885-025-13808-7
Citations
4
Primary Topic
Wnt/β-catenin signaling in development and cancer
Type
article
Field-Weighted Citation Impact
3.22
Controls
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article

CGREF1 facilitates the cell proliferation, migration and invasion of hepatocellular carcinoma cells via regulation of EIF3H/ Wnt/β-Catenin signaling axis

Dongkai Gao, Jinna Yang, Jun Zheng, Zumo Zhou et al.
4 citations
BMC Cancer
Wnt/β-catenin signaling in development and cancer
3.22
article

CGREF1 facilitates the cell proliferation, migration and invasion of hepatocellular carcinoma cells via regulation of EIF3H/ Wnt/β-Catenin signaling axis

Dongkai Gao, Jinna Yang, Jun Zheng, Zumo Zhou, Lin Chen
article en
4 citations

Abstract

CGREF1 is upregulated in HCC and acted as an oncogene through the CGREF1/EIF3H/Wnt/β-Catenin signaling axis. These findings suggest that CGREF1 may emerge as a potential therapeutic target for HCC.

BMC CancerVol. 25(1)
Zhuhai People's Hospital (CN)
Openalex Percentile: Top 9%
Wnt/β-catenin signaling in development and cancer
3.22
DOIOpen Access PDFOpenAlex
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CGREF1 facilitates the cell proliferation, migration and invasion of hepatocellular carcinoma cells via regulation of EIF3H/ Wnt/β-Catenin signaling axis — Dongkai Gao, Jinna Yang, et al. · BMC Cancer (2025) | TGRS Research Map | TGRS