Protection Against Pneumonia Induced by Vaccination with Fimbriae Subunits from Klebsiella pneumoniae
The results suggest that both type 1 and type 3 fimbriae contribute to protection against <i>K. pneumoniae</i> lung infection, inducing antibodies that bind to the bacteria and favoring Complement deposition and clearance by the host, while inhibiting biofilm formation.
Authors
- Lucas Assoni (ORCID: https://orcid.org/0000-0002-0324-3425)
- Beatriz Ferreira (ORCID: https://orcid.org/0000-0001-6845-7881)
- Lúcio Fábio Caldas Ferraz (ORCID: https://orcid.org/0000-0002-3818-3215)
- Monalisa Martins Trentini (ORCID: https://orcid.org/0000-0002-3207-8967)
- Anders Håkansson (ORCID: https://orcid.org/0000-0002-2834-6009)
- Juliana Baboghlian (ORCID: https://orcid.org/0009-0004-4363-270X)
- Lucas Miguel de Carvalho (ORCID: https://orcid.org/0000-0002-8766-0452)
- Grégory Rodrigo (ORCID: https://orcid.org/0000-0003-0067-1106)
- José Aires Pereira (ORCID: https://orcid.org/0000-0003-3937-7182)
- Raquel Girardello (ORCID: https://orcid.org/0000-0002-7117-0651)
- Thiago Rojas Converso (ORCID: https://orcid.org/0000-0001-5631-4541)
- Carlos Augusto Real Martinez (ORCID: https://orcid.org/0000-0001-8088-427X)
- Michelle Darrieux (ORCID: https://orcid.org/0000-0002-7829-3435)
- Isabelle Ciaparin
Institutions
- Lund University (SE)
- Instituto Butantan (BR)
- Universidade São Francisco (BR)
Publication Details
- Journal
- Vaccines
- Published
- 2025-03-11
- DOI
- https://doi.org/10.3390/vaccines13030303
- Citations
- 6
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 3.55
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior