Influence of Adipose Tissue on Ocular Inflammation
Our patient had rapid improvements in his ocular pathology that correlated with a notable reduction in body fat percentage. We propose that the immunological changes associated with obesity contributed to a proinflammatory ocular state that improved with weight loss. His case highlights that additional research is warranted to explore the etiopathogenic mechanisms of adipokines derived from white adipose tissue on major organ systems, including the eye.
Authors
- Kimberly Cabrera (ORCID: https://orcid.org/0000-0002-2385-5568)
- Raquel Goldhardt (ORCID: https://orcid.org/0000-0003-3140-6794)
- Anat Galor (ORCID: https://orcid.org/0000-0002-3026-6155)
- Normila Barthelemy
Institutions
- University of Miami (US)
- Veterans Health Administration (US)
- Miami Dermatology and Laser Institute (US)
Publication Details
- Journal
- Cornea
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1097/ico.0000000000003848
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Veterans Affairs
- Research to Prevent Blindness
- Biomedical Laboratory Research and Development, VA Office of Research and Development
- National Institutes of Health
- Rehabilitation Research and Development Service
- National Eye Institute