The virome investigation of the globally endangered Eld’s deer (Rucervus eldii) on Hainan Island, China
Eld's deer (Rucervus eldii) is a rare and globally endangered tropical Southeast Asian deer species. There is no research on pathogens in Eld's deer in Hainan, China. This study aimed to understand the virus diversity and novel viruses in Eld's deer, and provided important epidemiological baseline information for conservation of this endangered species. 33 nasal swabs, 33 anal swabs, and 9 wound (bitten by ticks) swabs were collected from 33 wild Eld's deer in a nature reserve in Hainan, which constituted into 5 pools. Based on next-generation sequencing (NGS) and macrogenomic analysis, there were differences in the 5 pools of viral reads, while the overall viral reads were closely related to mammals. The novel papillomavirus (PsPV-HMU-1) and Circular Rep-encoding (replication-associated protein encoding) single-stranded DNA (CRESS DNA) virus (PsaCV-HMU-1) were identified in Eld's deer, with amino acid homology of the less than 77.20% of the L1 and less than 45.43% of the rep, respectively. PsPV-HMU-1 and PsaCV-HMU-1 are relatively independent on their phylogenetic trees, and with the overall prevalence of 24.24% (8/33) and 3.03% (1/33) in Eld's deer, respectively. Our results expanded the viral genomic information and host range, and implied that it is necessary for continued epidemiological surveillance in order to understand pathogenicity and the potential for cross-species transmission of viruses in wild Eld's deer.
Authors
- Xiaoyuan Hu (ORCID: https://orcid.org/0009-0007-8233-1143)
- Qingqing Lu
- Gang Lü (ORCID: https://orcid.org/0000-0001-8017-2192)
- Feifei Yin (ORCID: https://orcid.org/0000-0001-6195-0614)
- Xuming Qi
- Gaoyu Wang (ORCID: https://orcid.org/0000-0002-6423-2914)
- Guangxu Ren (ORCID: https://orcid.org/0000-0003-2378-260X)
- Xiuji Cui
- Chuanning Tang (ORCID: https://orcid.org/0000-0001-5413-6470)
- Jie Dong (ORCID: https://orcid.org/0000-0003-0493-1665)
- Xiaoming Tan (ORCID: https://orcid.org/0000-0002-7375-3674)
- Haoxiang Su (ORCID: https://orcid.org/0009-0007-1057-5499)
- Jian Yang (ORCID: https://orcid.org/0000-0002-8826-5198)
- Ruoyan Peng
- Jiaqi Li (ORCID: https://orcid.org/0000-0001-6966-222X)
- Yu Li (ORCID: https://orcid.org/0000-0002-2246-8005)
- Zihan Li (ORCID: https://orcid.org/0000-0002-0101-977X)
- Yun Zhang (ORCID: https://orcid.org/0000-0002-4157-2131)
- Dandan Zheng (ORCID: https://orcid.org/0000-0002-3025-3557)
- Mingming Zhao (ORCID: https://orcid.org/0009-0002-3205-5471)
- Chuan Tian (ORCID: https://orcid.org/0009-0009-6444-0500)
- Yi Huang (ORCID: https://orcid.org/0000-0001-6585-5243)
- Youyou Li (ORCID: https://orcid.org/0000-0001-8185-4750)
- Lina Niu (ORCID: https://orcid.org/0000-0003-4134-5753)
- Yoon‐Seok Chang (ORCID: https://orcid.org/0000-0003-3157-0447)
- Fan Yang (ORCID: https://orcid.org/0000-0002-8111-4880)
Institutions
- Guiyang Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fanjingshan National Nature Reserve (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- 458th Hospital PLA (CN)
- Hainan Medical University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1038/s41598-025-92781-4
- Citations
- 1
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Natural Science Foundation of China