Epilepsy Risk Associated With the Receipt of General Anesthesia Relative to Neuraxial Anesthesia

The effects of general anesthesia may take multiple years to become significantly associated with an increased risk of epilepsy. However, our findings are likely affected by other factors, such as unmeasured differences between the anesthesia cohorts, types of surgical procedures, and the occurrence of epilepsy risk factors during follow-up. Future research should explore whether there is effect modification between specific surgical procedures and control for the onset of epilepsy risk factors after anesthesia receipt.

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Publication Details

Journal
Neurology
Published
2025-03-11
DOI
https://doi.org/10.1212/wnl.0000000000213469
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Epilepsy Risk Associated With the Receipt of General Anesthesia Relative to Neuraxial Anesthesia

Tresah C. Antaya, R. Grace Couper, Miguel Arango, Jorge G. Burneo et al.
Neurology
Epilepsy research and treatment
article

Epilepsy Risk Associated With the Receipt of General Anesthesia Relative to Neuraxial Anesthesia

Tresah C. Antaya, R. Grace Couper, Miguel Arango, Jorge G. Burneo, Philip M. Jones, Melody Lam, Mauricio Giraldo
article en

Abstract

The effects of general anesthesia may take multiple years to become significantly associated with an increased risk of epilepsy. However, our findings are likely affected by other factors, such as unmeasured differences between the anesthesia cohorts, types of surgical procedures, and the occurrence of epilepsy risk factors during follow-up. Future research should explore whether there is effect modification between specific surgical procedures and control for the onset of epilepsy risk factors after anesthesia receipt.

NeurologyVol. 104(7)
Western University (CA), London Health Sciences Centre (CA), Mayo Clinic in Florida (US)
Openalex Percentile: Top 94%
Epilepsy research and treatment
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