Fusobacterium nucleatum confirmed in gastric biopsies of patients without Helicobacter pylori
Three hundred patients with gastroduodenal disorders, including gastritis, duodenal ulcer, or gastric cancer, were included. One hundred and eighty (60%) patients were negative and 120 (40%) positive for H. pylori. Associations between the presence of H. pylori and age, gender, or other demographics were statistically insignificant (p > 0.05). The prevalence of F. nucleatum infection was determined for the two patient categories: 215 patients (72%) were positive for F. nucleatum; of these cases, 95 showed evidence of, and 120 lacked, concomitant H. pylori infection. Gastric biopsies obtained from patients with gastric cancer but negative for H. pylori revealed a significant prevalence of F. nucleatum infection.
Authors
- Negin Kamali (ORCID: https://orcid.org/0000-0002-8718-2614)
- Mojgan Forootan (ORCID: https://orcid.org/0000-0002-5101-5806)
- Farid Rahimi (ORCID: https://orcid.org/0000-0002-0920-8188)
- Amin Talebi Bezmin Abadi (ORCID: https://orcid.org/0000-0002-3979-8975)
Institutions
- Australian National University (AU)
- Tarbiat Modares University (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Research Notes
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s13104-025-07165-8
- Citations
- 4
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 8.03