Ursolic Acid‐Bonded Magnetic Nanoparticles Catalyzed the One‐Pot Synthesis of New Hexahydroquinoline‐3‐carboxamides
Abstract In this research, we present an effective method for synthesizing new derivatives of hexahydroquinoline‐3‐carboxamides through a one‐pot synthesis using formylarylsulfonates, dimedone or 1,3‐cyclohexanedione, acetoacetanilide, and ammonium acetate in high to excellent yield in EtOH at reflux conditions. This method utilizes ursolic acid (UA)‐bonded magnetic nanoparticles (nano‐Fe 3 O 4 @UA) as a catalyst. The method offers several advantages, including high yield, short reaction time, and simplicity, making it an attractive and efficient option in the emerging field of hexahydroquinolines synthesis.
Authors
- Fatemeh Azmian Moghadam (ORCID: https://orcid.org/0009-0005-4010-9478)
- Masoud Mokhtary (ORCID: https://orcid.org/0000-0003-3763-7139)
- Leila Asadpour
- Tahereh Moradhosseini
Institutions
- Guilan University of Medical Sciences (IR)
- Islamic Azad University Rasht Branch (IR)
Publication Details
- Journal
- ChemistrySelect
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/slct.202405798
- Citations
- 1
- Primary Topic
- Multicomponent Synthesis of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.94