Efficacy of atezolizumab combined with platinum and etoposide in the treatment of extrapulmonary neuroendocrine carcinoma

The addition of atezolizumab to EP did not improve PFS and OS in extrapulmonary NEC patients but did result in a higher response rate. Moreover, an NLR above 3 at diagnosis was identified as a poor prognostic factor for OS.

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Publication Details

Journal
The Oncologist
Published
2025-03-01
DOI
https://doi.org/10.1093/oncolo/oyae372
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy of atezolizumab combined with platinum and etoposide in the treatment of extrapulmonary neuroendocrine carcinoma

Jiun‐I Lai, I‐Wei Ho, San‐Chi Chen, Yi‐Ping Hung et al.
1 links
The Oncologist
Neuroendocrine Tumor Research Advances
article

Efficacy of atezolizumab combined with platinum and etoposide in the treatment of extrapulmonary neuroendocrine carcinoma

Jiun‐I Lai, I‐Wei Ho, San‐Chi Chen, Yi‐Ping Hung, Nai‐Jung Chiang, Peter Mu‐Hsin Chang, Ming‐Huang Chen
article en

Abstract

The addition of atezolizumab to EP did not improve PFS and OS in extrapulmonary NEC patients but did result in a higher response rate. Moreover, an NLR above 3 at diagnosis was identified as a poor prognostic factor for OS.

The OncologistVol. 30(3)
National Yang Ming Chiao Tung University (TW), Taipei Veterans General Hospital (TW), National Yang Ming Chiao Tung University (TW)
Taiwan Cancer Clinic Foundation, Taipei Veterans General Hospital, National Science and Technology Council
No poverty
Openalex Percentile: Top 93%
Neuroendocrine Tumor Research Advances
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