Identification and validation of a CD4+ T cell-related prognostic model to predict immune responses in stage III-IV colorectal cancer
The CD4<sup>+</sup> T cell-related prognostic signature established in the study can predict the prognosis and the response to immunotherapy in stage III-IV CRC patients. Our findings provide new insights for tumor immunotherapy of advanced CRC patients.
Authors
- Weining Zhu (ORCID: https://orcid.org/0000-0003-4981-9183)
- Fei Xu (ORCID: https://orcid.org/0000-0003-3346-7689)
- Lan Liu (ORCID: https://orcid.org/0000-0002-2860-0943)
- Mengting Li
- Yuanyuan Lu (ORCID: https://orcid.org/0000-0002-2050-5167)
- Qiu Zhao
- Yu Raymond Shao
Institutions
- Wuhan University (CN)
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Tongren Hospital (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Wuhan Third Hospital (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-03-11
- DOI
- https://doi.org/10.1186/s12876-025-03716-2
- Citations
- 6
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 6.27
Funders
- Natural Science Foundation of Hubei Province
- Fundamental Research Funds for the Central Universities
- National Key Clinical Specialty Discipline Construction Program of China