<scp>UFMylation</scp> Modulates <scp>OFIP</scp> Stability and Centrosomal Localization
OFIP is identified as a novel substrate for UFMylation. UFL1-mediated OFIP UFMylation is essential for its stability and centrosomal localization in HeLa cells. However, these effects are not observed in RPE1 cells, highlighting cell type-specific heterogeneity in the role of OFIP UFMylation.
Authors
- Jie Ran (ORCID: https://orcid.org/0000-0002-0744-7126)
- Mulin Yang (ORCID: https://orcid.org/0000-0001-9951-0411)
- Dengwen Li (ORCID: https://orcid.org/0000-0002-4573-7191)
- Jie Di
- Dan Dong (ORCID: https://orcid.org/0000-0002-9872-0051)
- Zhiyang Zhao
Institutions
- Nankai University (CN)
- Shandong Normal University (CN)
Publication Details
- Journal
- Journal of Clinical Laboratory Analysis
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1002/jcla.70004
- Citations
- 2
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- National Natural Science Foundation of China