Exploration of Circadian Clock‐Related Genes in the Pathogenesis of Psoriatic Arthritis to Identify Potential Therapeutic Targets From Multi‐Omics Insight: A Mendelian Randomization Study
This study suggests altered expression of circadian clock genes and proteins, including HLA-DQB1, ITPR3, GABBR1, IL4, OIP5-AS1, GCKR, CSNK2B, and STAT3, as factors contributing to the increased risk of PsA.
Authors
- Yifei Wang
- Aimei Liu (ORCID: https://orcid.org/0000-0003-4968-9577)
- Zhen Qin (ORCID: https://orcid.org/0009-0007-5797-3590)
- Sha Yi
- Wuda Huoshen
Institutions
- Chengdu Medical College (CN)
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
Publication Details
- Journal
- International Journal of Rheumatic Diseases
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1111/1756-185x.70158
- Citations
- 3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 5.45