Low-dose Radiation Improves Tumor Immune Microenvironment, Enhancing the Effects of Anti-CTLA-4 Therapy.
LDR has the ability to alter the immune microenvironment of tumors by promoting the production of IFN. Additionally, when combined with anti-CTLA-4, whole-body LDR can effectively suppress tumor growth in mice. The finding is of potential clinical significance and deserves further exploration.
Authors
- Jigang Dong (ORCID: https://orcid.org/0000-0002-6314-6512)
- Sha Sha (ORCID: https://orcid.org/0000-0002-4514-5671)
- Ying Qi
Institutions
- Shuozhou Central Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-30
- DOI
- https://doi.org/10.22034/iji.2025.103258.2825
- Citations
- 3
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 4.08