Associations of Ferritin and Folate Status With Clinical Outcomes in Childhood Cancer Patients: A Prospective Cohort Study

Paediatric cancer patients undergoing treatment exhibit high ferritin and reduced folate levels. Elevated ferritin is linked to increased toxicity and negative clinical outcomes, highlighting the importance of regular assessment and monitoring of both folate and ferritin. Implementing routine monitoring for these biomarkers could help mitigate adverse effects associated with treatment. Large-scale population-based studies and clinical trials are now warranted.

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Institutions

Publication Details

Journal
Pediatric Blood & Cancer
Published
2025-03-07
DOI
https://doi.org/10.1002/pbc.31645
Citations
1
Primary Topic
Childhood Cancer Survivors' Quality of Life
Type
article
Field-Weighted Citation Impact
3.49
Controls
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article

Associations of Ferritin and Folate Status With Clinical Outcomes in Childhood Cancer Patients: A Prospective Cohort Study

Kalum Withey, Ilenia Paciarotti, Raquel Revuelta Iniesta, Mark Brougham et al.
1 citations
Pediatric Blood & Cancer
Childhood Cancer Survivors' Quality of Life
3.49
article

Associations of Ferritin and Folate Status With Clinical Outcomes in Childhood Cancer Patients: A Prospective Cohort Study

Kalum Withey, Ilenia Paciarotti, Raquel Revuelta Iniesta, Mark Brougham, David C. Wilson, Jane McKenzie
article en
1 citations

Abstract

Paediatric cancer patients undergoing treatment exhibit high ferritin and reduced folate levels. Elevated ferritin is linked to increased toxicity and negative clinical outcomes, highlighting the importance of regular assessment and monitoring of both folate and ferritin. Implementing routine monitoring for these biomarkers could help mitigate adverse effects associated with treatment. Large-scale population-based studies and clinical trials are now warranted.

Pediatric Blood & CancerVol. 72(6)
University of Exeter (GB), Royal Hospital for Children (GB), Royal Hospital for Sick Children (GB), University of Edinburgh (GB)
Zero hunger
Openalex Percentile: Top 11%
Childhood Cancer Survivors' Quality of Life
3.49
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Associations of Ferritin and Folate Status With Clinical Outcomes in Childhood Cancer Patients: A Prospective Cohort Study — Kalum Withey, Ilenia Paciarotti, et al. · Pediatric Blood & Cancer (2025) | TGRS Research Map | TGRS