Associations of Ferritin and Folate Status With Clinical Outcomes in Childhood Cancer Patients: A Prospective Cohort Study
Paediatric cancer patients undergoing treatment exhibit high ferritin and reduced folate levels. Elevated ferritin is linked to increased toxicity and negative clinical outcomes, highlighting the importance of regular assessment and monitoring of both folate and ferritin. Implementing routine monitoring for these biomarkers could help mitigate adverse effects associated with treatment. Large-scale population-based studies and clinical trials are now warranted.
Authors
- Kalum Withey
- Ilenia Paciarotti
- Raquel Revuelta Iniesta (ORCID: https://orcid.org/0000-0002-5534-7146)
- Mark Brougham (ORCID: https://orcid.org/0000-0001-8048-7362)
- David C. Wilson (ORCID: https://orcid.org/0000-0003-0879-1129)
- Jane McKenzie
Institutions
- University of Exeter (GB)
- Royal Hospital for Children (GB)
- Royal Hospital for Sick Children (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1002/pbc.31645
- Citations
- 1
- Primary Topic
- Childhood Cancer Survivors' Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 3.49