Activation of SIRT1 by Hydroxysafflor Yellow A Attenuates Chronic Unpredictable Mild Stress‐Induced Microglia Activation and Iron Death in Depressed Rats

HSYA exerts an antidepressant-like effect by inhibiting microglia activation in the hippocampus and inducing SIRT1/Nrf2/NF-kB signaling.

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Publication Details

Journal
Brain and Behavior
Published
2025-03-01
DOI
https://doi.org/10.1002/brb3.70385
Citations
3
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
1.73
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article

Activation of SIRT1 by Hydroxysafflor Yellow A Attenuates Chronic Unpredictable Mild Stress‐Induced Microglia Activation and Iron Death in Depressed Rats

Ping Yang, Zhiqiang Liu, Jianhui Shangguan, Jianle He et al.
3 citations
Brain and Behavior
Tryptophan and brain disorders
1.73
article

Activation of SIRT1 by Hydroxysafflor Yellow A Attenuates Chronic Unpredictable Mild Stress‐Induced Microglia Activation and Iron Death in Depressed Rats

Ping Yang, Zhiqiang Liu, Jianhui Shangguan, Jianle He, Lingling Jiang, Min He
article en
3 citations

Abstract

HSYA exerts an antidepressant-like effect by inhibiting microglia activation in the hippocampus and inducing SIRT1/Nrf2/NF-kB signaling.

Brain and BehaviorVol. 15(3)
First Affiliated Hospital of Jiangxi Medical College (CN), Jiangxi Provincial People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 18%
Tryptophan and brain disorders
1.73
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